Board-certified dermatologist markKAHF mark (Korea Accreditation Program for Hospitals Serving Foreign Patients)Led by a board-certified dermatologist
Personal diagnosis · Accountable care
Ministry of Health and Welfare
KAHF-accredited hospital

DM DERMATOLOGY

CellREDM

ECM SKIN BOOSTER

A skin booster focused on
the structural components that support skin

CellREDM is an ECM skin booster made by turning dermis from human skin, with its cells removed, into very small particles.

Side profile of a model with clear, glowing skin

ECM stands for extracellular matrix. The extracellular matrix is the structural component that fills the space between cells in the dermis and supports the skin. Collagen and elastin are typical examples. CellREDM is made by HansBiomed. The manufacturer describes it as a skin booster that adds these structural components to the dermis.

The raw material of CellREDM is human acellular dermal matrix (hADM), a material obtained from donated human skin. For this reason, in Korea it is regulated as a human tissue product, not as a drug or medical device. We include this on the page so you can choose knowing where the material comes from and how it is regulated.

At DM Dermatology in Apgujeong, we first check your skin condition and medical history during the consultation. Then we decide the treatment area, injection amount, and interval. Results and recovery vary from person to person.

  • Extracellular matrix (ECM)
  • Human acellular dermal matrix
  • Microparticles
  • Dermal injection

IN NUMBERS

CellREDM by the numbers

  • Volume

    10cc

    DM Dermatology
    standard CellREDM volume

  • Particle

    75µm or less

    Particle size of the standard product,
    as stated by the manufacturer (0.075mm)

  • ECM

    3

    Main components of the ECM
    Collagen · elastin · GAG

A model with clear, even skin touching her cheek

CHECK LIST

If your skin's foundation concerns you,
ask for a consultation

  • Feels thinner

    Your skin looks thinner than before and less firm.

  • Texture · fine lines

    Your skin texture is uneven, and fine lines around the eyes and on the cheeks bother you.

  • Next step after hydration care

    You have had hydration-focused treatments and want to look after the skin's foundation too.

  • Comparing ingredients

    With so many ingredients, such as hyaluronic acid, PN, and ECM, you want to know the differences.

  • Checking the source material

    You want to know first how material from humans is made and regulated.

Whether the treatment is right for you is decided after we check your skin condition and medical history at your visit.

HOW IT WORKS

How extracellular matrix components
are added to the dermis

The dermis is the layer beneath the epidermis that supports the skin. The spaces between cells in the dermis are filled with collagen, elastin, and glycosaminoglycans (GAGs). GAGs are sugar components that hold water. With age and UV exposure, this structure is known to decrease and become looser.

Human acellular dermal matrix is material made by removing the cellular components from the dermis of donated human skin. This process is called decellularization. Acellular dermis has been used as a graft material in burn and wound treatment and in reconstructive surgery. CellREDM is a product in which this material is finely processed so it can be injected.

  • ECMExtracellular matrixThe structural component that fills the space between cells in the dermis and supports the skin.
  • hADMHuman acellular dermal matrixDermis from which a tissue bank has removed the cells, after donor screening and infection testing.
  • Micro­particleMicroparticlesFinely processed so it can be injected. Particle size differs by product.
  • DermisInjected in portions into the dermisSmall amounts are placed at many points with a fine needle so it spreads evenly.
3D illustration of microparticles placed in portions into the dermis of a skin cross-section with a fine needle, with one particle enlarged to show a mesh of collagen and elastin fibers
A simplified drawing of microparticles in the dermis.

SKIN BOOSTER

How skin boosters differ by ingredient

ECM (hADM)-basedHyaluronic acid (HA)-basedPolynucleotide (PN)-based
Main ingredientDermis from donated human skin with the cells removedHyaluronic acidDNA fragments from salmon and other sources
How it is described to workDescribed as adding extracellular matrix components to the dermisBinds with water to add moisture to the dermisDescribed as supporting the activity of fibroblasts (the cells that make collagen)
Regulatory category in KoreaHuman tissueMedical deviceMedical device
Examples on DM Dermatology's menuCellREDM, Re2OAqua Glow Injection, SkinViveRejuran

This table summarizes differences in ingredients and how they work. It does not mean one is better than another. We choose one, or plan them together, based on your skin condition and concerns.

PROCESS

The CellREDM treatment process

The method and time depend on your skin condition. We explain the details during your consultation.

  1. A medical staff member examining a patient's skin under a magnifying lamp

    step 01

    Consultation and skin check

    We check your skin thickness, texture, and areas of concern. We ask about medications you take, allergies, immune-related conditions, pregnancy or breastfeeding, and past treatments.

  2. Cream being spread thinly over the face of a patient lying down

    step 02

    Cleansing · disinfection · numbing

    We remove your makeup and disinfect the treatment area. Numbing is used to reduce pain. We explain the numbing method during your consultation.

  3. A gloved medical staff member injecting a skin booster into the cheek with a fine needle

    step 03

    Product preparation and dermal injection

    Just before treatment, the product is prepared so it can be injected. Using a fine needle, we place it in small amounts at many points in the dermis. The amount for each area is adjusted to your skin condition.

  4. A nurse soothing the cheek with a cool pad after treatment

    step 04

    Soothing and going-home instructions

    If needed, the treated area is cooled to soothe it. You go home after receiving aftercare instructions.

AFTER CARE

Know what to expect after treatment

  1. Day of treatment

    Redness, swelling, or small raised bumps may appear at injection sites. Do not rub them; cool them instead.

  2. 1–3 days

    Redness and swelling usually settle within a few days. During this time, avoid saunas, alcohol, and intense exercise.

  3. 1–2 weeks

    If you bruise, it may last until about this time. If a lump you can feel stays for a long time, contact the clinic.

  4. Before the next session

    We decide the timing and interval of the next session based on your skin condition and progress.

Progress varies from person to person. If you have symptoms you did not expect, contact the clinic.

INFORMATION

Treatment info

  • Procedure timeInjection 20–30 minPlus 30–40 min for numbing cream
  • NumbingNumbing creamReduces the stinging feeling
  • RecoveryRedness · swelling 1–3 daysBruises, if any, 1–2 weeks
  • Daily lifeMakeup from the next daySkip saunas and alcohol for a few days
  • Interval · Sessions3 sessions, 3–4 weeks apartAdjusted to your skin condition
  • Volume10ccDM Dermatology standard

These are general guidelines and vary from person to person. DM Dermatology sets your treatment schedule after an examination.

Caution

Aftercare and
what you should know

Keep irritation to your skin low until redness and swelling settle.

  1. 01
    Do not rub the treated area

    On the day of treatment, do not press hard on or rub the injected area. Skip facial massage for a few days too.

  2. 02
    Makeup from the next day

    Usually, avoid makeup on the day of treatment and start lightly from the next day. Wash your face gently with a mild product.

  3. 03
    Avoid heat, alcohol, and intense exercise

    Until redness and swelling settle, avoid saunas, hot compresses, alcohol, and intense exercise. Increased blood circulation can make swelling and bruising worse.

  4. 04
    Sun protection

    Apply sunscreen when you go out. While redness remains, avoid strong sunlight.

  5. 05
    Space out other treatments

    For treatments that cause skin reactions, such as laser or peels, set the interval with our medical staff first.

  6. 06
    Contact us right away about unusual symptoms

    If pain keeps getting worse, the area becomes swollen and hot, or the skin changes color, contact the clinic right away.

Side effects and precautions to know
  • Redness, swelling, pain, tenderness to the touch, itching, bruising, or injection marks may occur in the treated area. These usually settle within a few days, and bruises may last 1–2 weeks.
  • Injection sites may rise into small bumps, or a lump you can feel (nodule) may form. These usually shrink over time, but rarely they may remain for months or need treatment.
  • Rarely, inflammation or infection may develop. Injection treatments can trigger lip herpes (cold sore blisters) again. In darker skin tones, pigmentation may remain.
  • CellREDM is made from material that comes from human skin. The cellular components are removed during processing, but allergic or immune reactions may rarely occur. Even with donor screening and infection testing, the risk of disease transmission is only very low; it cannot be said to be zero.
  • With facial injections, very rarely, if injected material enters or presses on a blood vessel, serious complications such as skin necrosis or reduced vision may occur. If pain keeps getting worse, the skin turns white or bluish-black, or your vision becomes blurry, contact the clinic right away.
  • Tell us before treatment if you are pregnant or breastfeeding, have inflammation or infection in the treatment area, have an immune-related condition, take immunosuppressants, or have a history of severe allergies. Blood-thinning medicines such as aspirin or anticoagulants can make you bruise easily. Do not stop any medicine on your own; talk with the doctor who prescribed it.

Results, duration, and recovery vary from person to person with skin condition and lifestyle.

Dr. Shin Young-ik, Medical Director, board-certified dermatologist

DM DOCTOR

A board-certified dermatologist as medical director
Personal diagnosis · Accountable care

Thorough care from a board-certified dermatologist with over 20 years of treating skin

At DM Dermatology, our medical director, a board-certified dermatologist, examines your skin in person and plans treatment around your concerns and daily life.

Dr. Shin Young-ik Medical Director · Board-Certified Dermatologist

  • M.S., Hanyang University College of Medicine
  • Adjunct Professor, Hanyang University
  • Full Member, Korean Dermatological Association
  • Clinical Fellowship in Dermatology, Jefferson Medical College (Thomas Jefferson University), USA

Care by a board-certified dermatologistPatients here are seen by a dermatologist certified by the Ministry of Health and Welfare

Meet our doctor

FAQ

01What is CellREDM made from?

CellREDM is a skin booster made from human acellular dermal matrix (hADM). The cells are removed from the dermis of donated human skin, and the structural components that remain, such as collagen and elastin, are processed into very small particles. It is made by HansBiomed.

02Is CellREDM approved by Korea's Ministry of Food and Drug Safety?

CellREDM is known to be regulated as a human tissue product, not as a drug or medical device item. Human tissue is handled by tissue banks licensed by the Ministry of Food and Drug Safety, following standards for donor screening, infection testing, and processing and storage. This oversight is different in nature from product approval, which reviews effectiveness as a skin booster.

03Is it safe if the ingredient comes from human skin?

Donated skin goes through donor screening and infection testing, and cellular components are removed during processing. These measures lower the risk, but the possibility of disease transmission or immune reactions cannot be said to be zero. If you have allergies or immune-related conditions, be sure to tell us during the consultation.

04How is CellREDM different from Rejuran?

Rejuran is a skin booster whose main ingredient is DNA fragments (PN) from salmon and other sources. CellREDM's raw material is the structural components (ECM) of dermis obtained from human skin. They differ in raw material and in how they are described to work; neither can be said to be better. We choose one, or plan them together, based on your skin condition and concerns.

05Are CellREDM and Re2O the same kind of product?

Both are classified as ECM skin boosters made by processing human acellular dermal matrix (hADM). The manufacturer and product makeup differ. DM Dermatology offers both products, and we explain which product suits you after looking at your skin during the consultation.

06How many CellREDM sessions do I need, and how far apart?

Injectable skin boosters are usually planned as several sessions a few weeks apart. The interval and number of CellREDM sessions are decided based on your skin thickness, areas of concern, and other treatment plans. We explain the plan during your consultation.

07How long do CellREDM results last?

How long results last depends on skin condition, age, and lifestyle. We cannot promise a fixed period; we decide when to have the next treatment while watching your progress.

08Will I get numbing for CellREDM?

Because it is an injection treatment, there is a stinging feeling, so numbing cream is usually applied before treatment. How much you feel varies by person and area. DM Dermatology explains its numbing method during your consultation.

09Can I go to work the day after CellREDM?

Daily activities such as office work are usually possible after treatment. However, redness, injection marks, or bruises may remain for a few days, so try not to schedule it right before an important event. Avoid saunas and intense exercise until swelling settles.

10What does the 10cc CellREDM at DM Dermatology in Apgujeong refer to?

10cc is DM Dermatology's standard volume for CellREDM. How much to place in which areas of the face is decided after looking at your skin. We explain the product makeup we use during your consultation.

CONSULTATION

Consultation comes first

Before any treatment is chosen, a board-certified dermatologist checks your skin in person.

DM Dermatology, 4F, 579-1 Sinsa-dong, Gangnam-gu, Seoul

From Apgujeong Station (Line 3) Exit 5, walk straight for 50 m. 4th floor of the A Twosome Place building

Weekdays
am 10:00 - pm 07:00
Saturday
am 10:00 - pm 04:30
Lunch break
pm 01:00 - pm 02:00
Sun & holidays
By appointment only
  • Subway

    3Apgujeong StationExit 5

    Walk straight for 50 m · 2 min on foot · 4th floor of the A Twosome Place building

  • Bus

    Apgujeong Station Exit 4 · Exit 32310523429

    Blue bus147 · 148 · 240 · 463 · 343Green bus4211

    Kwanglim Church · Hyundai High School2310323104

    Blue bus143 · 240 · 345 · 472Green bus3011 · 4312 · 4318

  • By car

    Search in your navigation app158 Apgujeong-ro, Gangnam-gu디엠피부과의원

    Use the building’s underground parking · Parking available in the building

WeChat consultation

DM Dermatology WeChat QR code

WeChat ID : dmderma

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