
DM DERMATOLOGY
CellREDM
ECM SKIN BOOSTER
A skin booster focused on
the structural components that support skin
CellREDM is an ECM skin booster made by turning dermis from human skin, with its cells removed, into very small particles.

ECM stands for extracellular matrix. The extracellular matrix is the structural component that fills the space between cells in the dermis and supports the skin. Collagen and elastin are typical examples. CellREDM is made by HansBiomed. The manufacturer describes it as a skin booster that adds these structural components to the dermis.
The raw material of CellREDM is human acellular dermal matrix (hADM), a material obtained from donated human skin. For this reason, in Korea it is regulated as a human tissue product, not as a drug or medical device. We include this on the page so you can choose knowing where the material comes from and how it is regulated.
At DM Dermatology in Apgujeong, we first check your skin condition and medical history during the consultation. Then we decide the treatment area, injection amount, and interval. Results and recovery vary from person to person.
- Extracellular matrix (ECM)
- Human acellular dermal matrix
- Microparticles
- Dermal injection
IN NUMBERS
CellREDM by the numbers
Volume
10cc
DM Dermatology
standard CellREDM volumeParticle
75µm or less
Particle size of the standard product,
as stated by the manufacturer (0.075mm)ECM
3
Main components of the ECM
Collagen · elastin · GAG

CHECK LIST
If your skin's foundation concerns you,
ask for a consultation
- Feels thinner
Your skin looks thinner than before and less firm.
- Texture · fine lines
Your skin texture is uneven, and fine lines around the eyes and on the cheeks bother you.
- Next step after hydration care
You have had hydration-focused treatments and want to look after the skin's foundation too.
- Comparing ingredients
With so many ingredients, such as hyaluronic acid, PN, and ECM, you want to know the differences.
- Checking the source material
You want to know first how material from humans is made and regulated.
Whether the treatment is right for you is decided after we check your skin condition and medical history at your visit.
HOW IT WORKS
How extracellular matrix components
are added to the dermis
The dermis is the layer beneath the epidermis that supports the skin. The spaces between cells in the dermis are filled with collagen, elastin, and glycosaminoglycans (GAGs). GAGs are sugar components that hold water. With age and UV exposure, this structure is known to decrease and become looser.
Human acellular dermal matrix is material made by removing the cellular components from the dermis of donated human skin. This process is called decellularization. Acellular dermis has been used as a graft material in burn and wound treatment and in reconstructive surgery. CellREDM is a product in which this material is finely processed so it can be injected.
- ECMExtracellular matrixThe structural component that fills the space between cells in the dermis and supports the skin.
- hADMHuman acellular dermal matrixDermis from which a tissue bank has removed the cells, after donor screening and infection testing.
- MicroparticleMicroparticlesFinely processed so it can be injected. Particle size differs by product.
- DermisInjected in portions into the dermisSmall amounts are placed at many points with a fine needle so it spreads evenly.

SKIN BOOSTER
How skin boosters differ by ingredient
| ECM (hADM)-based | Hyaluronic acid (HA)-based | Polynucleotide (PN)-based | |
|---|---|---|---|
| Main ingredient | Dermis from donated human skin with the cells removed | Hyaluronic acid | DNA fragments from salmon and other sources |
| How it is described to work | Described as adding extracellular matrix components to the dermis | Binds with water to add moisture to the dermis | Described as supporting the activity of fibroblasts (the cells that make collagen) |
| Regulatory category in Korea | Human tissue | Medical device | Medical device |
| Examples on DM Dermatology's menu | CellREDM, Re2O | Aqua Glow Injection, SkinVive | Rejuran |
This table summarizes differences in ingredients and how they work. It does not mean one is better than another. We choose one, or plan them together, based on your skin condition and concerns.
PROCESS
The CellREDM treatment process
The method and time depend on your skin condition. We explain the details during your consultation.

step 01
Consultation and skin check
We check your skin thickness, texture, and areas of concern. We ask about medications you take, allergies, immune-related conditions, pregnancy or breastfeeding, and past treatments.

step 02
Cleansing · disinfection · numbing
We remove your makeup and disinfect the treatment area. Numbing is used to reduce pain. We explain the numbing method during your consultation.

step 03
Product preparation and dermal injection
Just before treatment, the product is prepared so it can be injected. Using a fine needle, we place it in small amounts at many points in the dermis. The amount for each area is adjusted to your skin condition.

step 04
Soothing and going-home instructions
If needed, the treated area is cooled to soothe it. You go home after receiving aftercare instructions.
AFTER CARE
Know what to expect after treatment
- Day of treatment
Redness, swelling, or small raised bumps may appear at injection sites. Do not rub them; cool them instead.
- 1–3 days
Redness and swelling usually settle within a few days. During this time, avoid saunas, alcohol, and intense exercise.
- 1–2 weeks
If you bruise, it may last until about this time. If a lump you can feel stays for a long time, contact the clinic.
- Before the next session
We decide the timing and interval of the next session based on your skin condition and progress.
Progress varies from person to person. If you have symptoms you did not expect, contact the clinic.
INFORMATION
Treatment info
- Procedure timeInjection 20–30 minPlus 30–40 min for numbing cream
- NumbingNumbing creamReduces the stinging feeling
- RecoveryRedness · swelling 1–3 daysBruises, if any, 1–2 weeks
- Daily lifeMakeup from the next daySkip saunas and alcohol for a few days
- Interval · Sessions3 sessions, 3–4 weeks apartAdjusted to your skin condition
- Volume10ccDM Dermatology standard
These are general guidelines and vary from person to person. DM Dermatology sets your treatment schedule after an examination.
Caution
Aftercare and
what you should know
Keep irritation to your skin low until redness and swelling settle.

- 01Do not rub the treated area
On the day of treatment, do not press hard on or rub the injected area. Skip facial massage for a few days too.
- 02Makeup from the next day
Usually, avoid makeup on the day of treatment and start lightly from the next day. Wash your face gently with a mild product.
- 03Avoid heat, alcohol, and intense exercise
Until redness and swelling settle, avoid saunas, hot compresses, alcohol, and intense exercise. Increased blood circulation can make swelling and bruising worse.
- 04Sun protection
Apply sunscreen when you go out. While redness remains, avoid strong sunlight.
- 05Space out other treatments
For treatments that cause skin reactions, such as laser or peels, set the interval with our medical staff first.
- 06Contact us right away about unusual symptoms
If pain keeps getting worse, the area becomes swollen and hot, or the skin changes color, contact the clinic right away.
- Redness, swelling, pain, tenderness to the touch, itching, bruising, or injection marks may occur in the treated area. These usually settle within a few days, and bruises may last 1–2 weeks.
- Injection sites may rise into small bumps, or a lump you can feel (nodule) may form. These usually shrink over time, but rarely they may remain for months or need treatment.
- Rarely, inflammation or infection may develop. Injection treatments can trigger lip herpes (cold sore blisters) again. In darker skin tones, pigmentation may remain.
- CellREDM is made from material that comes from human skin. The cellular components are removed during processing, but allergic or immune reactions may rarely occur. Even with donor screening and infection testing, the risk of disease transmission is only very low; it cannot be said to be zero.
- With facial injections, very rarely, if injected material enters or presses on a blood vessel, serious complications such as skin necrosis or reduced vision may occur. If pain keeps getting worse, the skin turns white or bluish-black, or your vision becomes blurry, contact the clinic right away.
- Tell us before treatment if you are pregnant or breastfeeding, have inflammation or infection in the treatment area, have an immune-related condition, take immunosuppressants, or have a history of severe allergies. Blood-thinning medicines such as aspirin or anticoagulants can make you bruise easily. Do not stop any medicine on your own; talk with the doctor who prescribed it.
Results, duration, and recovery vary from person to person with skin condition and lifestyle.

DM DOCTOR
A board-certified dermatologist as medical director
Personal diagnosis · Accountable care
Thorough care from a board-certified dermatologist with over 20 years of treating skin
At DM Dermatology, our medical director, a board-certified dermatologist, examines your skin in person and plans treatment around your concerns and daily life.
Dr. Shin Young-ik Medical Director · Board-Certified Dermatologist
- M.S., Hanyang University College of Medicine
- Adjunct Professor, Hanyang University
- Full Member, Korean Dermatological Association
- Clinical Fellowship in Dermatology, Jefferson Medical College (Thomas Jefferson University), USA
Care by a board-certified dermatologistPatients here are seen by a dermatologist certified by the Ministry of Health and Welfare
FAQ
01What is CellREDM made from?
CellREDM is a skin booster made from human acellular dermal matrix (hADM). The cells are removed from the dermis of donated human skin, and the structural components that remain, such as collagen and elastin, are processed into very small particles. It is made by HansBiomed.
02Is CellREDM approved by Korea's Ministry of Food and Drug Safety?
CellREDM is known to be regulated as a human tissue product, not as a drug or medical device item. Human tissue is handled by tissue banks licensed by the Ministry of Food and Drug Safety, following standards for donor screening, infection testing, and processing and storage. This oversight is different in nature from product approval, which reviews effectiveness as a skin booster.
03Is it safe if the ingredient comes from human skin?
Donated skin goes through donor screening and infection testing, and cellular components are removed during processing. These measures lower the risk, but the possibility of disease transmission or immune reactions cannot be said to be zero. If you have allergies or immune-related conditions, be sure to tell us during the consultation.
04How is CellREDM different from Rejuran?
Rejuran is a skin booster whose main ingredient is DNA fragments (PN) from salmon and other sources. CellREDM's raw material is the structural components (ECM) of dermis obtained from human skin. They differ in raw material and in how they are described to work; neither can be said to be better. We choose one, or plan them together, based on your skin condition and concerns.
05Are CellREDM and Re2O the same kind of product?
Both are classified as ECM skin boosters made by processing human acellular dermal matrix (hADM). The manufacturer and product makeup differ. DM Dermatology offers both products, and we explain which product suits you after looking at your skin during the consultation.
06How many CellREDM sessions do I need, and how far apart?
Injectable skin boosters are usually planned as several sessions a few weeks apart. The interval and number of CellREDM sessions are decided based on your skin thickness, areas of concern, and other treatment plans. We explain the plan during your consultation.
07How long do CellREDM results last?
How long results last depends on skin condition, age, and lifestyle. We cannot promise a fixed period; we decide when to have the next treatment while watching your progress.
08Will I get numbing for CellREDM?
Because it is an injection treatment, there is a stinging feeling, so numbing cream is usually applied before treatment. How much you feel varies by person and area. DM Dermatology explains its numbing method during your consultation.
09Can I go to work the day after CellREDM?
Daily activities such as office work are usually possible after treatment. However, redness, injection marks, or bruises may remain for a few days, so try not to schedule it right before an important event. Avoid saunas and intense exercise until swelling settles.
10What does the 10cc CellREDM at DM Dermatology in Apgujeong refer to?
10cc is DM Dermatology's standard volume for CellREDM. How much to place in which areas of the face is decided after looking at your skin. We explain the product makeup we use during your consultation.
CONSULTATION
Consultation comes first
Before any treatment is chosen, a board-certified dermatologist checks your skin in person.
DM Dermatology, 4F, 579-1 Sinsa-dong, Gangnam-gu, Seoul
From Apgujeong Station (Line 3) Exit 5, walk straight for 50 m. 4th floor of the A Twosome Place building
- Weekdays
- am 10:00 - pm 07:00
- Saturday
- am 10:00 - pm 04:30
- Lunch break
- pm 01:00 - pm 02:00
- Sun & holidays
- By appointment only
- Subway
3Apgujeong StationExit 5
Walk straight for 50 m · 2 min on foot · 4th floor of the A Twosome Place building
- Bus
Apgujeong Station Exit 4 · Exit 32310523429
Blue bus147 · 148 · 240 · 463 · 343Green bus4211
Kwanglim Church · Hyundai High School2310323104
Blue bus143 · 240 · 345 · 472Green bus3011 · 4312 · 4318
- By car
Search in your navigation app158 Apgujeong-ro, Gangnam-gu디엠피부과의원
Use the building’s underground parking · Parking available in the building







