Board-certified dermatologist markKAHF mark (Korea Accreditation Program for Hospitals Serving Foreign Patients)Led by a board-certified dermatologist
Personal diagnosis · Accountable care
Ministry of Health and Welfare
KAHF-accredited hospital

DM DERMATOLOGY

NCTF135

ABOUT NCTF 135 HA

Hyaluronic acid
with added nutrients:
NCTF135

NCTF135 is an injectable solution of non-cross-linked hyaluronic acid with added ingredients such as vitamins, amino acids, and minerals. In this skin booster treatment, the solution is placed into the dermis in very small portions.

Still life of three small glass vials holding clear, sky-blue, and mint solutions, with a folded white towel, on white marble with reflections of water light

NCTF® 135 HA

Skin booster · NCTF135

The product is NCTF® 135 HA, made by FILLMED of France. Each glass vial contains 3mL. 3mL is the same amount as 3cc.

Hyaluronic acid is an ingredient that holds moisture in the skin. NCTF135 combines it with ingredients such as vitamins, amino acids, minerals, and coenzymes. DM Dermatology recommends a schedule of 3 sessions, 2 weeks–1 month apart.

Before treatment, DM Dermatology in Apgujeong first checks your skin condition, medications, allergies, and recent treatments. Then we decide the treatment area and method. Results and recovery vary from person to person.

  • Non-cross-linked hyaluronic acid
  • Vitamins · amino acids · minerals
  • 3mL per vial
  • 3 sessions, 2 weeks–1 month apart
A woman with her hair tied back, wearing a white sleeveless turtleneck knit, looking to the side in front of a bright white background with floating soap bubbles. Clear, glowing skin

CHECK

If you have these skin concerns

  • Fine lines

    Fine lines around your eyes and mouth stand out more after you put on makeup.

  • Elasticity

    Your skin looks thin and lacks firmness, so you are first looking into treatments that care for the skin's foundation.

  • Complexion

    Even after enough sleep, people often tell you your face looks dull and tired.

  • Glow

    Your skin texture is rough and lacks glow, so makeup does not go on smoothly.

  • Pores · texture

    Enlarged pores and rough texture bother you. If depressed acne scars are a concern, look into scar treatment as well.

Which treatment is right for you is decided after the doctor examines your skin.

HOW IT WORKS

Non-cross-linked hyaluronic acid
and nutrients

Hyaluronic acid is naturally present in the dermis, the layer beneath the epidermis that supports the skin. Because it holds water, hyaluronic acid plays a role in keeping moisture in the skin.

The hyaluronic acid in NCTF135 is non-cross-linked hyaluronic acid, meaning its chains are not bound together. Cross-linking is a process that binds hyaluronic acid chains together so they break down more slowly in the body. Non-cross-linked hyaluronic acid is a thin solution, so when it is placed in small droplets, it spreads through the dermis.

Vitamins, amino acids, minerals, coenzymes, nucleosides, and the antioxidant glutathione are added to it. The manufacturer explains that these ingredients create an environment where fibroblasts in the dermis can work well. Fibroblasts are the cells that make collagen and elastin.

3D illustration of a skin block. Six clear droplets line up in the shallow layer of the transparent dermis below a pink epidermis, each gathering pale purple granules and sky-blue water droplets. Below are ivory fibers, mint-colored fibroblasts, and cream-colored subcutaneous fat
  1. 1

    Epidermis The outermost layer of the skin. The fine needle passes through this layer to reach the dermis.

  2. 2

    Dermis The layer beneath the epidermis that gives the skin its elasticity and thickness. NCTF135 is placed in the shallow part of the dermis.

  3. 3

    Hyaluronic acid An ingredient that holds water. Because it is not cross-linked, it spreads through the dermis.

  4. 4

    Nutrients Ingredients such as vitamins, amino acids, minerals, and coenzymes. They come in the same vial as the hyaluronic acid.

  5. 5

    Fibroblasts Cells in the dermis that make collagen and elastin.

A simplified skin cross-section for explanation only. The actual ingredients and cells are too small to see.

INGREDIENTS

60 ingredients in one vial

Each 1mL contains 5mg of non-cross-linked hyaluronic acid. The six groups of ingredients below are added to it.

  • Vitamins

    12

    Vitamins
    A, C, E, the B group, and more

  • Amino Acids

    24

    Amino acids
    The building blocks of protein

  • Minerals

    6

    Minerals
    Calcium, potassium, magnesium, and more

  • Coenzymes

    6

    Coenzymes
    Substances that help enzymes work

  • Nucleosides

    5

    Nucleosides
    Building materials of DNA

  • Antioxidants

    6

    Glutathione and more
    Antioxidant and sugar components

60 in total, including hyaluronic acid.

COMPARE

Aqua Glow Injection and NCTF135:
what is different?

Both treatments place hyaluronic acid into the dermis in small portions. The difference is the other ingredients in the solution.

Aqua Glow InjectionHyaluronic acid skin booster
NCTF135Hyaluronic acid + nutrients
Hyaluronic acid
(cross-linked or non-cross-linked, depending on the product)
Main ingredientNon-cross-linked hyaluronic acid
(5mg per 1mL)
Centered on hyaluronic acidOther ingredients59 ingredients, including vitamins, amino acids, minerals, and coenzymes
Injected in small portions at many points in the dermisMethodInjected in very small amounts at many points in the shallow layer of the dermis
Redness and bumps for a few days; bruises rarely last 2 weeksTypical recoveryRedness and small bumps 1–2 days; bruises, if any, about 1 week
2–3 sessions, 2–4 weeks apartTypical number of sessions3 sessions, 2 weeks–1 month apart

This table only puts ingredients and schedules side by side. It does not mean one is better. Which treatment suits you is decided after we look at your skin at your visit.

GOALS

What NCTF135
aims to do

How much change appears, and when, varies from person to person with skin condition and lifestyle.

  1. Hydration in the skin

    Hyaluronic acid holds water, so it may help with hydration in skin that looks dry and tired.

  2. Shallow fine lines and skin texture

    This treatment addresses shallow fine lines and uneven skin texture. For deep wrinkles or sagging, other treatments may be a better fit.

  3. Complexion and glow

    When skin texture is even and hydration is good, it may help your complexion look clearer and more radiant.

  4. Scheduling with other treatments

    It can be planned together with laser, Botox (botulinum toxin), or filler on separate dates. The order and intervals are decided at your visit.

PROCESS

NCTF135
treatment process

Below is the general flow. We explain the actual order and method after your examination.

  • A woman who gets fine lines at the outer corners of her eyes when she smiles, touching them with her fingertips
    01

    Examination and skin check

    We look at your skin condition and areas of concern. We ask about medications (especially aspirin and anticoagulants), allergies, autoimmune diseases, pregnancy or breastfeeding, cold sores (lip herpes), and recent treatments.

  • A woman wearing a mint headband lies on a treatment bed while a medical staff member in a mint uniform applies cream around her mouth and chin with gloved hands
    02

    Cleansing and numbing cream

    We remove your makeup and disinfect your face. To reduce the sting, numbing cream is applied, followed by a wait of about 30 minutes.

  • Still life of treatment preparation: two glass vials of clear solution, a syringe without a needle, gauze, and sky-blue gloves on a white tray
    03

    Product preparation

    The solution in the vial is drawn into a syringe. A vial, once opened, is never reused for another person.

  • A gloved hand injecting small amounts into the cheek of a patient lying down with a very fine needle
    04

    Placing it in the dermis

    After checking where to inject, we use a fine needle or an injection device to place it in very small amounts at many points in the shallow layer of the dermis. Moles (nevi) and pus-filled acne spots are avoided.

  • A woman sitting on a sofa in a bright lounge, holding a white cold pack to her cheek
    05

    Soothing and going home

    If needed, cool pads cool the skin. You go home after hearing when you can wear makeup and what to watch for in daily life.

INFORMATION

NCTF135 treatment info

  • Procedure timeInjections 15–30 minPlus about 30 min with numbing cream on
  • NumbingNumbing creamA slight sting may remain
  • RecoveryRedness 1–2 daysSmall bumps also 1–2 days; bruises, if any, about 1 week
  • Daily lifeMakeup after 12 hoursNo alcohol or smoking for 1 week; no saunas, jjimjilbang, or strenuous exercise for 2 weeks
  • Interval · Sessions3 sessions, 2 weeks–1 month apartLater sessions are planned based on your skin
  • Volume3cc (one vial) per sessionThe treatment area is decided at your visit

These are general guidelines and vary from person to person. DM Dermatology lets you know your treatment schedule after an examination.

Caution

After NCTF135:
aftercare and precautions

Injection sites may be red and slightly raised for a few days. Please follow the care steps below.

  1. 01
    No makeup for 12 hours

    Do not wear makeup for 12 hours after treatment. Wash your face gently with lukewarm water, and do not rub with a towel.

  2. 02
    No pressing or rubbing

    Do not press the injection sites with your hands or rub them hard. Skip facial massage and massage devices for a few days too.

  3. 03
    No alcohol or smoking for 1 week

    Avoid alcohol and cigarettes for about a week.

  4. 04
    Avoid heat and sweat for 2 weeks

    Avoid saunas, jjimjilbang (Korean bathhouses), hot baths, and strenuous exercise for 2 weeks.

  5. 05
    Avoid sun and cold wind

    Do not stay long in strong sunlight or very cold wind. Apply sunscreen before going out.

  6. 06
    Contact us right away about warning signs

    If swelling and pain get worse every day, pus or blisters form, or a firm lump can be felt weeks later, contact the clinic right away.

Side effects and precautions to know
  • Redness, mild swelling, small bumps, and a stinging pain may occur at injection sites. The needle sites may bleed a little. These usually settle within a few hours to a few days.
  • Bruising may occur. It usually fades in about a week and can last close to 2 weeks at most. Blood-thinning medicines such as aspirin or anticoagulants can increase bruising and bleeding. Do not stop any medicine on your own; talk first with the doctor who prescribed it.
  • Because the needle passes through the skin, infection may rarely occur. If you have had lip herpes (cold sores), blisters may come back after treatment.
  • Because the solution mixes many ingredients, an allergy to any of them may rarely develop. Tell us if itching, hives, or severe swelling appears. Numbing cream can also cause redness or a hypersensitivity reaction.
  • Rarely, a firm lump (nodule) may form at an injection site, or a granuloma may form from long-lasting inflammation. The skin there may also change color or harden. Please let the clinic know even if a new lump is felt weeks later.
  • The solution is placed so that it does not enter blood vessels. If your eye becomes red or dry, or your vision becomes blurry after injection around the eyes, contact the clinic immediately.
  • This treatment is not given in these cases: a skin disease or inflammation in the treatment area, a history of autoimmune disease or current immune therapy, an allergy to any ingredient, age under 18, and pregnancy or breastfeeding.
  • Moles (nevi) and pus-filled acne spots are not injected. If the area has had non-absorbable filler, tell us in advance. It is not done on the same day as a medium-depth or deeper peel or resurfacing.

The degree of change, recovery time, and bruising and swelling vary from person to person with skin condition and lifestyle.

Dr. Shin Young-ik, Medical Director, board-certified dermatologist

DM DOCTOR

A board-certified dermatologist first checks
your skin and your medications

We look at your skin thickness, areas of concern, and recent treatments, then decide the treatment areas and schedule. If you take blood-thinning medicine or have allergies, we review them together before treatment.

Dr. Shin Young-ik Medical Director · Board-Certified Dermatologist

  • M.S., Hanyang University College of Medicine
  • Adjunct Professor, Hanyang University
  • Full Member, Korean Dermatological Association
  • Clinical Fellowship in Dermatology, Jefferson Medical College (Thomas Jefferson University), USA
Meet our doctor

FAQ

01What is NCTF135?

NCTF135 is a skin booster treatment that places a solution of non-cross-linked hyaluronic acid mixed with ingredients such as vitamins, amino acids, and minerals into the dermis. The product is NCTF® 135 HA, made by FILLMED of France. Very small amounts are placed at many points on the face.

02What ingredients are in NCTF 135HA?

Each 1mL contains 5mg of non-cross-linked hyaluronic acid. Added to this are 12 vitamins, 24 amino acids, 6 minerals, 6 coenzymes, 5 nucleosides, and 6 others, including glutathione. Including hyaluronic acid, there are 60 in total.

03How is NCTF different from Aqua Glow Injection?

Both treatments place hyaluronic acid into the dermis in small portions. The difference is that NCTF135 is a solution of non-cross-linked hyaluronic acid mixed with ingredients such as vitamins, amino acids, and minerals. This does not mean one is better; we choose based on your skin condition and concerns.

04How is NCTF different from Rejuran?

Rejuran's main ingredient is a DNA ingredient (PN) obtained from salmon. NCTF135's main ingredients are non-cross-linked hyaluronic acid and various nutrients. The injection method is similar, but the raw materials differ; which treatment suits you is decided at your visit.

05How many NCTF sessions do I need, and how often?

DM Dermatology recommends a schedule of 3 sessions, 2 weeks to 1 month apart. Within this range, the interval is set to fit your recovery and personal schedule. After the 3 sessions, we discuss the next schedule again based on your skin.

06Does NCTF hurt? Is numbing used?

The fine needle pricks many points, so there is a stinging feeling. Numbing cream is usually applied about 30 minutes before the injections to reduce the sting. How much it hurts varies by person and area, and thin skin such as the eye area may be more sensitive.

07How long do bumps and bruises last after NCTF?

Small bumps and redness at injection sites usually settle in 1–2 days. Bruises, if any, last about 1 week and can last close to 2 weeks at most. If raised spots or lumps last a long time, do not touch them; contact the clinic.

08When can I wear makeup and wash my face after NCTF?

Do not wear makeup for 12 hours after treatment. Wash your face gently with lukewarm water, and do not rub the injection sites. Avoid alcohol and smoking for 1 week, and saunas, jjimjilbang, and strenuous exercise for 2 weeks.

09Is there anyone who should not get NCTF?

It is not given if you are pregnant or breastfeeding, or under 18. It is also not given if you have had an autoimmune disease or are receiving immune therapy, have an allergy to an ingredient, or have a skin disease or inflammation in the treatment area. If you take blood-thinning medicine or have had lip herpes (cold sores), be sure to tell us at your visit.

10How much is the 3cc of NCTF135 at DM Dermatology in Apgujeong?

3cc is 3mL, the amount in one vial of NCTF® 135 HA. Often, one vial is divided evenly between both sides of the face in one session. The areas and amounts are decided after we look at your skin at your visit.

CONSULTATION

Consultation comes first

Before any treatment is chosen, a board-certified dermatologist checks your skin in person.

DM Dermatology, 4F, 579-1 Sinsa-dong, Gangnam-gu, Seoul

From Apgujeong Station (Line 3) Exit 5, walk straight for 50 m. 4th floor of the A Twosome Place building

Weekdays
am 10:00 - pm 07:00
Saturday
am 10:00 - pm 04:30
Lunch break
pm 01:00 - pm 02:00
Sun & holidays
By appointment only
  • Subway

    3Apgujeong StationExit 5

    Walk straight for 50 m · 2 min on foot · 4th floor of the A Twosome Place building

  • Bus

    Apgujeong Station Exit 4 · Exit 32310523429

    Blue bus147 · 148 · 240 · 463 · 343Green bus4211

    Kwanglim Church · Hyundai High School2310323104

    Blue bus143 · 240 · 345 · 472Green bus3011 · 4312 · 4318

  • By car

    Search in your navigation app158 Apgujeong-ro, Gangnam-gu디엠피부과의원

    Use the building’s underground parking · Parking available in the building

WeChat consultation

DM Dermatology WeChat QR code

WeChat ID : dmderma

Scan the QR code in the WeChat app, or search for our ID and add us.