
DM DERMATOLOGY
NCTF135
ABOUT NCTF 135 HA
Hyaluronic acid
with added nutrients:
NCTF135
NCTF135 is an injectable solution of non-cross-linked hyaluronic acid with added ingredients such as vitamins, amino acids, and minerals. In this skin booster treatment, the solution is placed into the dermis in very small portions.

NCTF® 135 HA
Skin booster · NCTF135
The product is NCTF® 135 HA, made by FILLMED of France. Each glass vial contains 3mL. 3mL is the same amount as 3cc.
Hyaluronic acid is an ingredient that holds moisture in the skin. NCTF135 combines it with ingredients such as vitamins, amino acids, minerals, and coenzymes. DM Dermatology recommends a schedule of 3 sessions, 2 weeks–1 month apart.
Before treatment, DM Dermatology in Apgujeong first checks your skin condition, medications, allergies, and recent treatments. Then we decide the treatment area and method. Results and recovery vary from person to person.
- Non-cross-linked hyaluronic acid
- Vitamins · amino acids · minerals
- 3mL per vial
- 3 sessions, 2 weeks–1 month apart

CHECK
If you have these skin concerns
- Fine lines
Fine lines around your eyes and mouth stand out more after you put on makeup.
- Elasticity
Your skin looks thin and lacks firmness, so you are first looking into treatments that care for the skin's foundation.
- Complexion
Even after enough sleep, people often tell you your face looks dull and tired.
- Glow
Your skin texture is rough and lacks glow, so makeup does not go on smoothly.
- Pores · texture
Enlarged pores and rough texture bother you. If depressed acne scars are a concern, look into scar treatment as well.
Which treatment is right for you is decided after the doctor examines your skin.
HOW IT WORKS
Non-cross-linked hyaluronic acid
and nutrients
Hyaluronic acid is naturally present in the dermis, the layer beneath the epidermis that supports the skin. Because it holds water, hyaluronic acid plays a role in keeping moisture in the skin.
The hyaluronic acid in NCTF135 is non-cross-linked hyaluronic acid, meaning its chains are not bound together. Cross-linking is a process that binds hyaluronic acid chains together so they break down more slowly in the body. Non-cross-linked hyaluronic acid is a thin solution, so when it is placed in small droplets, it spreads through the dermis.
Vitamins, amino acids, minerals, coenzymes, nucleosides, and the antioxidant glutathione are added to it. The manufacturer explains that these ingredients create an environment where fibroblasts in the dermis can work well. Fibroblasts are the cells that make collagen and elastin.

- 1
Epidermis The outermost layer of the skin. The fine needle passes through this layer to reach the dermis.
- 2
Dermis The layer beneath the epidermis that gives the skin its elasticity and thickness. NCTF135 is placed in the shallow part of the dermis.
- 3
Hyaluronic acid An ingredient that holds water. Because it is not cross-linked, it spreads through the dermis.
- 4
Nutrients Ingredients such as vitamins, amino acids, minerals, and coenzymes. They come in the same vial as the hyaluronic acid.
- 5
Fibroblasts Cells in the dermis that make collagen and elastin.
INGREDIENTS
60 ingredients in one vial
Each 1mL contains 5mg of non-cross-linked hyaluronic acid. The six groups of ingredients below are added to it.
Vitamins
12
Vitamins
A, C, E, the B group, and moreAmino Acids
24
Amino acids
The building blocks of proteinMinerals
6
Minerals
Calcium, potassium, magnesium, and moreCoenzymes
6
Coenzymes
Substances that help enzymes workNucleosides
5
Nucleosides
Building materials of DNAAntioxidants
6
Glutathione and more
Antioxidant and sugar components
60 in total, including hyaluronic acid.
COMPARE
Aqua Glow Injection and NCTF135:
what is different?
Both treatments place hyaluronic acid into the dermis in small portions. The difference is the other ingredients in the solution.
(cross-linked or non-cross-linked, depending on the product)Main ingredientNon-cross-linked hyaluronic acid
(5mg per 1mL)
This table only puts ingredients and schedules side by side. It does not mean one is better. Which treatment suits you is decided after we look at your skin at your visit.
GOALS
What NCTF135
aims to do
How much change appears, and when, varies from person to person with skin condition and lifestyle.
Hydration in the skin
Hyaluronic acid holds water, so it may help with hydration in skin that looks dry and tired.
Shallow fine lines and skin texture
This treatment addresses shallow fine lines and uneven skin texture. For deep wrinkles or sagging, other treatments may be a better fit.
Complexion and glow
When skin texture is even and hydration is good, it may help your complexion look clearer and more radiant.
Scheduling with other treatments
It can be planned together with laser, Botox (botulinum toxin), or filler on separate dates. The order and intervals are decided at your visit.
PROCESS
NCTF135
treatment process
Below is the general flow. We explain the actual order and method after your examination.
01Examination and skin check
We look at your skin condition and areas of concern. We ask about medications (especially aspirin and anticoagulants), allergies, autoimmune diseases, pregnancy or breastfeeding, cold sores (lip herpes), and recent treatments.
02Cleansing and numbing cream
We remove your makeup and disinfect your face. To reduce the sting, numbing cream is applied, followed by a wait of about 30 minutes.
03Product preparation
The solution in the vial is drawn into a syringe. A vial, once opened, is never reused for another person.
04Placing it in the dermis
After checking where to inject, we use a fine needle or an injection device to place it in very small amounts at many points in the shallow layer of the dermis. Moles (nevi) and pus-filled acne spots are avoided.
05Soothing and going home
If needed, cool pads cool the skin. You go home after hearing when you can wear makeup and what to watch for in daily life.
INFORMATION
NCTF135 treatment info
- Procedure timeInjections 15–30 minPlus about 30 min with numbing cream on
- NumbingNumbing creamA slight sting may remain
- RecoveryRedness 1–2 daysSmall bumps also 1–2 days; bruises, if any, about 1 week
- Daily lifeMakeup after 12 hoursNo alcohol or smoking for 1 week; no saunas, jjimjilbang, or strenuous exercise for 2 weeks
- Interval · Sessions3 sessions, 2 weeks–1 month apartLater sessions are planned based on your skin
- Volume3cc (one vial) per sessionThe treatment area is decided at your visit
These are general guidelines and vary from person to person. DM Dermatology lets you know your treatment schedule after an examination.
Caution
After NCTF135:
aftercare and precautions
Injection sites may be red and slightly raised for a few days. Please follow the care steps below.

- 01No makeup for 12 hours
Do not wear makeup for 12 hours after treatment. Wash your face gently with lukewarm water, and do not rub with a towel.
- 02No pressing or rubbing
Do not press the injection sites with your hands or rub them hard. Skip facial massage and massage devices for a few days too.
- 03No alcohol or smoking for 1 week
Avoid alcohol and cigarettes for about a week.
- 04Avoid heat and sweat for 2 weeks
Avoid saunas, jjimjilbang (Korean bathhouses), hot baths, and strenuous exercise for 2 weeks.
- 05Avoid sun and cold wind
Do not stay long in strong sunlight or very cold wind. Apply sunscreen before going out.
- 06Contact us right away about warning signs
If swelling and pain get worse every day, pus or blisters form, or a firm lump can be felt weeks later, contact the clinic right away.
- Redness, mild swelling, small bumps, and a stinging pain may occur at injection sites. The needle sites may bleed a little. These usually settle within a few hours to a few days.
- Bruising may occur. It usually fades in about a week and can last close to 2 weeks at most. Blood-thinning medicines such as aspirin or anticoagulants can increase bruising and bleeding. Do not stop any medicine on your own; talk first with the doctor who prescribed it.
- Because the needle passes through the skin, infection may rarely occur. If you have had lip herpes (cold sores), blisters may come back after treatment.
- Because the solution mixes many ingredients, an allergy to any of them may rarely develop. Tell us if itching, hives, or severe swelling appears. Numbing cream can also cause redness or a hypersensitivity reaction.
- Rarely, a firm lump (nodule) may form at an injection site, or a granuloma may form from long-lasting inflammation. The skin there may also change color or harden. Please let the clinic know even if a new lump is felt weeks later.
- The solution is placed so that it does not enter blood vessels. If your eye becomes red or dry, or your vision becomes blurry after injection around the eyes, contact the clinic immediately.
- This treatment is not given in these cases: a skin disease or inflammation in the treatment area, a history of autoimmune disease or current immune therapy, an allergy to any ingredient, age under 18, and pregnancy or breastfeeding.
- Moles (nevi) and pus-filled acne spots are not injected. If the area has had non-absorbable filler, tell us in advance. It is not done on the same day as a medium-depth or deeper peel or resurfacing.
The degree of change, recovery time, and bruising and swelling vary from person to person with skin condition and lifestyle.

DM DOCTOR
A board-certified dermatologist first checks
your skin and your medications
We look at your skin thickness, areas of concern, and recent treatments, then decide the treatment areas and schedule. If you take blood-thinning medicine or have allergies, we review them together before treatment.
Dr. Shin Young-ik Medical Director · Board-Certified Dermatologist
- M.S., Hanyang University College of Medicine
- Adjunct Professor, Hanyang University
- Full Member, Korean Dermatological Association
- Clinical Fellowship in Dermatology, Jefferson Medical College (Thomas Jefferson University), USA
FAQ
01What is NCTF135?
NCTF135 is a skin booster treatment that places a solution of non-cross-linked hyaluronic acid mixed with ingredients such as vitamins, amino acids, and minerals into the dermis. The product is NCTF® 135 HA, made by FILLMED of France. Very small amounts are placed at many points on the face.
02What ingredients are in NCTF 135HA?
Each 1mL contains 5mg of non-cross-linked hyaluronic acid. Added to this are 12 vitamins, 24 amino acids, 6 minerals, 6 coenzymes, 5 nucleosides, and 6 others, including glutathione. Including hyaluronic acid, there are 60 in total.
03How is NCTF different from Aqua Glow Injection?
Both treatments place hyaluronic acid into the dermis in small portions. The difference is that NCTF135 is a solution of non-cross-linked hyaluronic acid mixed with ingredients such as vitamins, amino acids, and minerals. This does not mean one is better; we choose based on your skin condition and concerns.
04How is NCTF different from Rejuran?
Rejuran's main ingredient is a DNA ingredient (PN) obtained from salmon. NCTF135's main ingredients are non-cross-linked hyaluronic acid and various nutrients. The injection method is similar, but the raw materials differ; which treatment suits you is decided at your visit.
05How many NCTF sessions do I need, and how often?
DM Dermatology recommends a schedule of 3 sessions, 2 weeks to 1 month apart. Within this range, the interval is set to fit your recovery and personal schedule. After the 3 sessions, we discuss the next schedule again based on your skin.
06Does NCTF hurt? Is numbing used?
The fine needle pricks many points, so there is a stinging feeling. Numbing cream is usually applied about 30 minutes before the injections to reduce the sting. How much it hurts varies by person and area, and thin skin such as the eye area may be more sensitive.
07How long do bumps and bruises last after NCTF?
Small bumps and redness at injection sites usually settle in 1–2 days. Bruises, if any, last about 1 week and can last close to 2 weeks at most. If raised spots or lumps last a long time, do not touch them; contact the clinic.
08When can I wear makeup and wash my face after NCTF?
Do not wear makeup for 12 hours after treatment. Wash your face gently with lukewarm water, and do not rub the injection sites. Avoid alcohol and smoking for 1 week, and saunas, jjimjilbang, and strenuous exercise for 2 weeks.
09Is there anyone who should not get NCTF?
It is not given if you are pregnant or breastfeeding, or under 18. It is also not given if you have had an autoimmune disease or are receiving immune therapy, have an allergy to an ingredient, or have a skin disease or inflammation in the treatment area. If you take blood-thinning medicine or have had lip herpes (cold sores), be sure to tell us at your visit.
10How much is the 3cc of NCTF135 at DM Dermatology in Apgujeong?
3cc is 3mL, the amount in one vial of NCTF® 135 HA. Often, one vial is divided evenly between both sides of the face in one session. The areas and amounts are decided after we look at your skin at your visit.
CONSULTATION
Consultation comes first
Before any treatment is chosen, a board-certified dermatologist checks your skin in person.
DM Dermatology, 4F, 579-1 Sinsa-dong, Gangnam-gu, Seoul
From Apgujeong Station (Line 3) Exit 5, walk straight for 50 m. 4th floor of the A Twosome Place building
- Weekdays
- am 10:00 - pm 07:00
- Saturday
- am 10:00 - pm 04:30
- Lunch break
- pm 01:00 - pm 02:00
- Sun & holidays
- By appointment only
- Subway
3Apgujeong StationExit 5
Walk straight for 50 m · 2 min on foot · 4th floor of the A Twosome Place building
- Bus
Apgujeong Station Exit 4 · Exit 32310523429
Blue bus147 · 148 · 240 · 463 · 343Green bus4211
Kwanglim Church · Hyundai High School2310323104
Blue bus143 · 240 · 345 · 472Green bus3011 · 4312 · 4318
- By car
Search in your navigation app158 Apgujeong-ro, Gangnam-gu디엠피부과의원
Use the building’s underground parking · Parking available in the building






